ABNORMAL IMAGING PRESENTATIONS OF EXTRAMEDULLARY HEMATOPOIESIS IN A 21-YEAR OLD AND 72-YEAR OLD FEMALE


Transcriptional immune suppression and up-regulation of double-stranded DNA damage and repair repertoires in ecDNA-containing tumors

Extrachromosomal DNA is a common cause of oncogene amplification in cancer.The non-chromosomal inheritance of ecDNA enables tumors to rapidly evolve, contributing to treatment resistance and poor outcome for patients.The transcriptional context in which ecDNAs arise and progress, including chromosomally-driven transcription, Program Timer is incomp

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